DKC1 Recombinant Rabbit mAb
Cat No.: ARM1604
Size:
Product Name: | DKC1 Recombinant Rabbit mAb |
Cat No.: | ARM1604 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,ICC/IF |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human DKC1 |
calculated molecular weight: | 58 kDa |
observed molecular weight: | 58 kDa |
genbank accession number: | O60832 |
gene id (ncbi): | 1736 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | DKC; CBF5; DKCX; NAP57; NOLA4; XAP101 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |