MRPS31 Recombinant Rabbit mAb
Cat No.: ARM1602
Size:
Product Name: | MRPS31 Recombinant Rabbit mAb |
Cat No.: | ARM1602 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB |
clonality: | Monoclonal |
recommended dilution: | WB |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human MRPS31 |
calculated molecular weight: | 45 kDa |
observed molecular weight: | 45 kDa |
genbank accession number: | Q92665 |
gene id (ncbi): | 10240 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | S31mt; IMOGN38; MRP-S31 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13. [provided by RefSeq, Jul 2008] |