TPP1 Recombinant Rabbit mAb
Cat No.: ARM1589
Size:
Product Name: | TPP1 Recombinant Rabbit mAb |
Cat No.: | ARM1589 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC |
clonality: | Monoclonal |
recommended dilution: | WB,IHC |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human TPP1 |
calculated molecular weight: | 61,35 kDa |
observed molecular weight: | 61,48 kDa |
genbank accession number: | O14773 |
gene id (ncbi): | 1200 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CLN2; GIG1; LPIC; SCAR7; TPP-1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008] |