NEDD4 Recombinant Rabbit mAb
Cat No.: ARM1564
Size:
Product Name: | NEDD4 Recombinant Rabbit mAb |
Cat No.: | ARM1564 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,FC,IP |
clonality: | Monoclonal |
recommended dilution: | WB,FC,IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human NEDD4 |
calculated molecular weight: | 149 kDa |
observed molecular weight: | 115 kDa |
genbank accession number: | P46934 |
gene id (ncbi): | 4734 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | RPF1; NEDD4-1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016] |