CD27 Recombinant Rabbit mAb
Cat No.: ARM1511
Size:
Product Name: | CD27 Recombinant Rabbit mAb |
Cat No.: | ARM1511 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,ICC/IF,FC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CD27 |
calculated molecular weight: | 29 kDa |
observed molecular weight: | 49 kDa |
genbank accession number: | P26842 |
gene id (ncbi): | 939 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | T14; S152; Tp55; TNFRSF7; S152. LPFS2 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] |