Prostaglandin E Synthase Recombinant Rabbit mAb
Cat No.: ARM1472
Size:
Product Name: | Prostaglandin E Synthase Recombinant Rabbit mAb |
Cat No.: | ARM1472 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB |
clonality: | Monoclonal |
recommended dilution: | WB |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Prostaglandin E Synthase |
calculated molecular weight: | 17 kDa |
observed molecular weight: | 17 kDa |
genbank accession number: | O14684 |
gene id (ncbi): | 9536 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | PGES; MPGES; PIG12; PP102; PP1294; MGST-IV; MGST1L1; TP53I12; mPGES-1; MGST1-L1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008] |