Retinoic Acid Receptor beta Recombinant Rabbit mAb
Cat No.: ARM1460
Size:
Product Name: | Retinoic Acid Receptor beta Recombinant Rabbit mAb |
Cat No.: | ARM1460 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,ICC/IF |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Retinoic Acid Receptor beta |
calculated molecular weight: | 51 kDa |
observed molecular weight: | 55 kDa |
genbank accession number: | P10826 |
gene id (ncbi): | 5915 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | HAP; RRB2; NR1B2; MCOPS12; RARbeta1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014] |