SIRT3 Recombinant Rabbit mAb
Cat No.: ARM1425
Size:
Product Name: | SIRT3 Recombinant Rabbit mAb |
Cat No.: | ARM1425 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC |
clonality: | Monoclonal |
recommended dilution: | WB,IHC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human SIRT3 |
calculated molecular weight: | 44 kDa |
observed molecular weight: | 28 kDa |
genbank accession number: | Q9NTG7 |
gene id (ncbi): | 23410 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | SIR2L3 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008] |