Factor D Recombinant Rabbit mAb
Cat No.: ARM1396
Size:
Product Name: | Factor D Recombinant Rabbit mAb |
Cat No.: | ARM1396 |
source: | Rabbit |
reactivity: | Human |
applications: | WB |
clonality: | Monoclonal |
recommended dilution: | WB |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human Factor D |
calculated molecular weight: | 27 kDa |
observed molecular weight: | 27 kDa |
genbank accession number: | P00746 |
gene id (ncbi): | 1675 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | DF; ADN; PFD; ADIPSIN |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] |