Nucleophosmin Recombinant Rabbit mAb
Cat No.: ARM1380
Size:
Product Name: | Nucleophosmin Recombinant Rabbit mAb |
Cat No.: | ARM1380 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,FC,IP |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,FC,IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Nucleophosmin |
calculated molecular weight: | 33 kDa |
observed molecular weight: | 38 kDa |
genbank accession number: | P06748 |
gene id (ncbi): | 4869 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | B23; NPM |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017] |