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LAT Recombinant Rabbit mAb

Cat No.: ARM1373
Size:
Product Name: LAT Recombinant Rabbit mAb
Cat No.: ARM1373
source: Rabbit
reactivity: Human
applications: WB,IHC,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human LAT
calculated molecular weight: 28 kDa
observed molecular weight: 36 kDa
genbank accession number: O43561
gene id (ncbi): 27040
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: LAT1; pp36; IMD52
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]