BLNK Recombinant Rabbit mAb
Cat No.: ARM1363
Size：
| Product Name: | BLNK Recombinant Rabbit mAb |
| Cat No.: | ARM1363 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human BLNK |
| calculated molecular weight: | 51 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | Q8WV28 |
| gene id (ncbi): | 29760 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] |