Ras Recombinant Rabbit mAb
Cat No.: ARM1357
Size:
Product Name: | Ras Recombinant Rabbit mAb |
Cat No.: | ARM1357 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,IP |
clonality: | Monoclonal |
recommended dilution: | WB,ICC/IF,IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Ras |
calculated molecular weight: | 22 kDa |
observed molecular weight: | 22 kDa |
genbank accession number: | P01111 |
gene id (ncbi): | 4893 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] |