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Ras Recombinant Rabbit mAb

Cat No.: ARM1357
Size:
Product Name: Ras Recombinant Rabbit mAb
Cat No.: ARM1357
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,IP
clonality: Monoclonal
recommended dilution: WB,ICC/IF,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Ras
calculated molecular weight: 22 kDa
observed molecular weight: 22 kDa
genbank accession number: P01111
gene id (ncbi): 4893
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1
category: Primary Ab
concentration: 1mg/ml
background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]