Cip4 Recombinant Rabbit mAb
Cat No.: ARM1329
Size：
| Product Name: | Cip4 Recombinant Rabbit mAb |
| Cat No.: | ARM1329 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Cip4 |
| calculated molecular weight: | 68 kDa |
| observed molecular weight: | 80 kDa |
| genbank accession number: | Q15642 |
| gene id (ncbi): | 9322 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | STP; CIP4; HSTP; STOT; TRIP-10 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. |