CYB5R3 Recombinant Rabbit mAb
Cat No.: ARM1311
Size:
Product Name: | CYB5R3 Recombinant Rabbit mAb |
Cat No.: | ARM1311 |
source: | Rabbit |
reactivity: | Human, Rat |
applications: | WB,IHC |
clonality: | Monoclonal |
recommended dilution: | WB,IHC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CYB5R3 |
calculated molecular weight: | 34 kDa |
observed molecular weight: | 34 kDa |
genbank accession number: | P00387 |
gene id (ncbi): | 1727 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | B5R; DIA1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010] |