PLSCR3 Recombinant Rabbit mAb
Cat No.: ARM1297
Size：
| Product Name: | PLSCR3 Recombinant Rabbit mAb |
| Cat No.: | ARM1297 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Monoclonal |
| recommended dilution: | WB |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human PLSCR3 |
| calculated molecular weight: | 32 kDa |
| observed molecular weight: | 32 kDa |
| genbank accession number: | Q9NRY6 |
| gene id (ncbi): | 57048 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Ca(2+)-dependent phospholipid scramblase 3 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. |