Cullin 1 Recombinant Rabbit mAb
Cat No.: ARM1274
Size:
Product Name: | Cullin 1 Recombinant Rabbit mAb |
Cat No.: | ARM1274 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,FC |
clonality: | Monoclonal |
recommended dilution: | WB,ICC/IF,FC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Cullin 1 |
calculated molecular weight: | 90 kDa |
observed molecular weight: | 90 kDa |
genbank accession number: | Q13616 |
gene id (ncbi): | 8454 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CUL1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346). In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. |