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Cullin 1 Recombinant Rabbit mAb

Cat No.: ARM1274
Size:
Product Name: Cullin 1 Recombinant Rabbit mAb
Cat No.: ARM1274
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,FC
clonality: Monoclonal
recommended dilution: WB,ICC/IF,FC
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Cullin 1
calculated molecular weight: 90 kDa
observed molecular weight: 90 kDa
genbank accession number: Q13616
gene id (ncbi): 8454
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CUL1
category: Primary Ab
concentration: 1mg/ml
background: Core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346). In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits.