GLCNE Recombinant Rabbit mAb
Cat No.: ARM1267
Size：
| Product Name: | GLCNE Recombinant Rabbit mAb |
| Cat No.: | ARM1267 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,ICC/IF,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,ICC/IF,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human GLCNE |
| calculated molecular weight: | 79 kDa |
| observed molecular weight: | 75 kDa |
| genbank accession number: | Q9Y223 |
| gene id (ncbi): | 10020 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NM; DMRV; IBM2; Uae1; GLCNE |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |