KDM4B/JMJD2B Recombinant Rabbit mAb
Cat No.: ARM1266
Size:
Product Name: | KDM4B/JMJD2B Recombinant Rabbit mAb |
Cat No.: | ARM1266 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,ICC/IF,FC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human KDM4B/JMJD2B |
calculated molecular weight: | 122 kDa |
observed molecular weight: | 150 kDa |
genbank accession number: | O94953 |
gene id (ncbi): | 23030 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | JMJD2B; TDRD14B |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | Histone demethylase that specifically demethylates --Lys-9-- of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 --Lys-4--, H3 --Lys-27--, H3 --Lys-36-- nor H4 --Lys-20--. Only able to demethylate trimethylated H3 --Lys-9--, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. |