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NQO1 Recombinant Rabbit mAb

Cat No.: ARM1264
Size:
Product Name: NQO1 Recombinant Rabbit mAb
Cat No.: ARM1264
source: Rabbit
reactivity: Human
applications: WB,IP
clonality: Monoclonal
recommended dilution: WB,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human NQO1
calculated molecular weight: 31 kDa
observed molecular weight: 31 kDa
genbank accession number: P15559
gene id (ncbi): 1728
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DTD; QR1; DHQU; DIA4; NMOR1; NMORI
category: Primary Ab
concentration: 1mg/ml
background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein--s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer--s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]