Skp1 Recombinant Rabbit mAb
Cat No.: ARM1261
Size：
| Product Name: | Skp1 Recombinant Rabbit mAb |
| Cat No.: | ARM1261 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,ICC/IF,FC |
| clonality: | Monoclonal |
| recommended dilution: | WB,ICC/IF,FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Skp1 |
| calculated molecular weight: | 19 kDa |
| observed molecular weight: | 19 kDa |
| genbank accession number: | P63208 |
| gene id (ncbi): | 6500 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008] |