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Cdk9 Recombinant Rabbit mAb

Cat No.: ARM1242
Size:
Product Name: Cdk9 Recombinant Rabbit mAb
Cat No.: ARM1242
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,IP
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Cdk9
calculated molecular weight: 43 kDa
observed molecular weight: 43 kDa
genbank accession number: P50750
gene id (ncbi): 1025
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: TAK; C-2k; CTK1; CDC2L4; PITALRE
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]