eIF3B Recombinant Rabbit mAb
Cat No.: ARM1225
Size：
| Product Name: | eIF3B Recombinant Rabbit mAb |
| Cat No.: | ARM1225 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human eIF3B |
| calculated molecular weight: | 93 kDa |
| observed molecular weight: | 117 kDa |
| genbank accession number: | P55884 |
| gene id (ncbi): | 8662 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. |