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L1CAM Recombinant Rabbit mAb

Cat No.: ARM1224
Size:
Product Name: L1CAM Recombinant Rabbit mAb
Cat No.: ARM1224
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Monoclonal
recommended dilution: WB,IHC
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human L1CAM
calculated molecular weight: 140 kDa
observed molecular weight: 140 kDa
genbank accession number: P32004
gene id (ncbi): 3897
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]