RAMP1 Recombinant Rabbit mAb
Cat No.: ARM1219
Size：
| Product Name: | RAMP1 Recombinant Rabbit mAb |
| Cat No.: | ARM1219 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,FC |
| clonality: | Monoclonal |
| recommended dilution: | WB,FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human RAMP1 |
| calculated molecular weight: | 17 kDa |
| observed molecular weight: | 17 kDa |
| genbank accession number: | O60894 |
| gene id (ncbi): | 10267 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Calcitonin-receptor-like receptor activity-modifying protein 1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |