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LEF1 Recombinant Rabbit mAb

Cat No.: ARM1181
Size:
Product Name: LEF1 Recombinant Rabbit mAb
Cat No.: ARM1181
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,FC
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human LEF1
calculated molecular weight: 44 kDa
observed molecular weight: 25-58 kDa
genbank accession number: Q9UJU2
gene id (ncbi): 51176
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: LEF-1; TCF10; TCF7L3; TCF1ALPHA
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]