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ATP6V1A Recombinant Rabbit mAb

Cat No.: ARM1178
Size:
Product Name: ATP6V1A Recombinant Rabbit mAb
Cat No.: ARM1178
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human ATP6V1A
calculated molecular weight: 68 kDa
observed molecular weight: 68 kDa
genbank accession number: P38606
gene id (ncbi): 523
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; ATP6V1A1
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c--, c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. [provided by RefSeq, Jul 2008]