MSH6 Recombinant Rabbit mAb
Cat No.: ARM1123
Size：
| Product Name: | MSH6 Recombinant Rabbit mAb |
| Cat No.: | ARM1123 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human MSH6 |
| calculated molecular weight: | 163 kDa |
| observed molecular weight: | 163 kDa |
| genbank accession number: | P52701 |
| gene id (ncbi): | 2956 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | GTBP; HSAP; p160; GTMBP; HNPCC5 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] |