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KAT1/HAT1 Recombinant Rabbit mAb

Cat No.: ARM1105
Size:
Product Name: KAT1/HAT1 Recombinant Rabbit mAb
Cat No.: ARM1105
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,IP
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human KAT1/HAT1
calculated molecular weight: 50 kDa
observed molecular weight: 45 kDa
genbank accession number: O14929
gene id (ncbi): 8520
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: KAT1
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]