PTF1A Recombinant Rabbit mAb
Cat No.: ARM1095
Size：
| Product Name: | PTF1A Recombinant Rabbit mAb |
| Cat No.: | ARM1095 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse PTF1A |
| calculated molecular weight: | 35 kDa |
| observed molecular weight: | 48 kDa |
| genbank accession number: | Q9QX98 |
| gene id (ncbi): | 19213 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | PTF1p48; bHLHa29; PTF1-p48 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5---CANNTG-3--. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates. |