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PKR Recombinant Rabbit mAb

Cat No.: ARM1087
Size:
Product Name: PKR Recombinant Rabbit mAb
Cat No.: ARM1087
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,FC,IP
clonality: Monoclonal
recommended dilution: WB,IHC,ICC/IF,FC,IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human PKR
calculated molecular weight: 62 kDa
observed molecular weight: 74 kDa
genbank accession number: P19525
gene id (ncbi): 5610
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PKR; PRKR; EIF2AK1; PPP1R83
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]