Kappa Opioid Receptor Recombinant Rabbit mAb
Cat No.: ARM1060
Size：
| Product Name: | Kappa Opioid Receptor Recombinant Rabbit mAb |
| Cat No.: | ARM1060 |
| source: | Rabbit |
| reactivity: | Mouse, Rat |
| applications: | WB,IHC,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of mouse Kappa Opioid Receptor |
| calculated molecular weight: | 43 kDa |
| observed molecular weight: | 60 kDa |
| genbank accession number: | P33534 |
| gene id (ncbi): | 18387 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | KOR; R21; KOR-1; MSL-1; Oprk2; K-OR-1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016] |