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hnRNP K Recombinant Rabbit mAb

Cat No.: ARM1022
Size:
Product Name: hnRNP K Recombinant Rabbit mAb
Cat No.: ARM1022
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC
clonality: Monoclonal
recommended dilution: WB,IHC
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human hnRNP K
calculated molecular weight: 51 kDa
observed molecular weight: 62 kDa
genbank accession number: P61978
gene id (ncbi): 3190
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: AUKS; CSBP; TUNP; HNRPK
category: Primary Ab
concentration: 1mg/ml
background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008]