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TFE3 Recombinant Rabbit mAb

Cat No.: ARM1012
Size:
Product Name: TFE3 Recombinant Rabbit mAb
Cat No.: ARM1012
source: Rabbit
reactivity: Human
applications: IHC,ICC/IF,FC
clonality: Monoclonal
recommended dilution: IHC,ICC/IF,FC
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human TFE3
calculated molecular weight: 62 kDa
observed molecular weight:
genbank accession number: P19532
gene id (ncbi): 7030
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: TFEA; RCCP2; RCCX1; bHLHe33
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]