MGMT Recombinant Rabbit mAb
Cat No.: ARM1009
Size：
| Product Name: | MGMT Recombinant Rabbit mAb |
| Cat No.: | ARM1009 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human MGMT |
| calculated molecular weight: | 22 kDa |
| observed molecular weight: | 22 kDa |
| genbank accession number: | P16455 |
| gene id (ncbi): | 4255 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | 6-O-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015] |