S100B Recombinant Rabbit mAb
Cat No.: ARM1004
Size：
| Product Name: | S100B Recombinant Rabbit mAb |
| Cat No.: | ARM1004 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB, IHC, ICC/IF, IP |
| clonality: | Monoclonal |
| recommended dilution: | WB, IHC, ICC/IF, IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human S100B |
| calculated molecular weight: | 11 kDa |
| observed molecular weight: | 11 kDa |
| genbank accession number: | P04271 |
| gene id (ncbi): | 6285 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NEF; S100; S100-B; S100beta |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer--s disease, Down--s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008] |