• Drop us a line for any questions: info@assayvector.com

FADD Recombinant Rabbit mAb

Cat No.: ARM1002
Size:
Product Name: FADD Recombinant Rabbit mAb
Cat No.: ARM1002
source: Rabbit
reactivity: Mouse, Rat
applications: WB, IHC, FC
clonality: Monoclonal
recommended dilution: WB, IHC, FC
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of mouse FADD
calculated molecular weight: 23 kDa
observed molecular weight: 28 kDa
genbank accession number: Q61160
gene id (ncbi): 14082
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: Mort1/FADD
category: Primary Ab
concentration: 1mg/ml
background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).