FADD Recombinant Rabbit mAb
Cat No.: ARM1002
Size:
Product Name: | FADD Recombinant Rabbit mAb |
Cat No.: | ARM1002 |
source: | Rabbit |
reactivity: | Mouse, Rat |
applications: | WB, IHC, FC |
clonality: | Monoclonal |
recommended dilution: | WB, IHC, FC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of mouse FADD |
calculated molecular weight: | 23 kDa |
observed molecular weight: | 28 kDa |
genbank accession number: | Q61160 |
gene id (ncbi): | 14082 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | Mort1/FADD |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity). |