Cyclin E2 Recombinant Rabbit mAb
Cat No.: ARM2894
Size：
| Product Name: | Cyclin E2 Recombinant Rabbit mAb |
| Cat No.: | ARM2894 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB, IHC, ICC/IF, FC |
| clonality: | Monoclonal |
| recommended dilution: | WB, IHC, ICC/IF, FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Cyclin E2 |
| calculated molecular weight: | 47 kDa |
| observed molecular weight: | 47 kDa |
| genbank accession number: | O96020 |
| gene id (ncbi): | 9134 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CYCE2 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008] |