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Bad Recombinant Rabbit mAb

Cat No.: ARM2873
Size:
Product Name: Bad Recombinant Rabbit mAb
Cat No.: ARM2873
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB, IHC, ICC/IF, FC, IP
clonality: Monoclonal
recommended dilution: WB, IHC, ICC/IF, FC, IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Bad
calculated molecular weight: 18 kDa
observed molecular weight: 23 kDa
genbank accession number: Q92934
gene id (ncbi): 572
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BBC2; BCL2L8
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]