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SMAC Recombinant Rabbit mAb

Cat No.: ARM2845
Size:
Product Name: SMAC Recombinant Rabbit mAb
Cat No.: ARM2845
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB, IHC, ICC/IF, FC, IP
clonality: Monoclonal
recommended dilution: WB, IHC, ICC/IF, FC, IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Smac/Diablo
calculated molecular weight: 27 kDa
observed molecular weight: 21 kDa
genbank accession number: Q9NR28
gene id (ncbi): 56616
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: SMAC; DFNA64
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]