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Cullin 3 Recombinant Rabbit mAb

Cat No.: ARM2842
Size:
Product Name: Cullin 3 Recombinant Rabbit mAb
Cat No.: ARM2842
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB, FC, IP
clonality: Monoclonal
recommended dilution: WB, FC, IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Cullin 3
calculated molecular weight: 89 kDa
observed molecular weight: 89 kDa
genbank accession number: Q13618
gene id (ncbi): 8452
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CUL-3; PHA2E
category: Primary Ab
concentration: 1mg/ml
background: This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]