PGK1 Recombinant Rabbit mAb
Cat No.: ARM2836
Size：
| Product Name: | PGK1 Recombinant Rabbit mAb |
| Cat No.: | ARM2836 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB, ICC/IF, FC |
| clonality: | Monoclonal |
| recommended dilution: | WB, ICC/IF, FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human PGK1 |
| calculated molecular weight: | 45 kDa |
| observed molecular weight: | 45 kDa |
| genbank accession number: | P00558 |
| gene id (ncbi): | 5230 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | PGKA; MIG10; HEL-S-68p |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014] |