Alkaline Phosphatase Recombinant Rabbit mAb
Cat No.: ARM2832
Size:
Product Name: | Alkaline Phosphatase Recombinant Rabbit mAb |
Cat No.: | ARM2832 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB, IHC, ICC/IF, FC, IP |
clonality: | Monoclonal |
recommended dilution: | WB, IHC, ICC/IF, FC, IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Alkaline Phosphatase, Tissue Non-Specific |
calculated molecular weight: | 57 kDa |
observed molecular weight: | 80 kDa |
genbank accession number: | P05186 |
gene id (ncbi): | 249 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | HOPS; TNAP; APTNAP; TNSALP; AP-TNAP |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015] |