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PKC delta Recombinant Rabbit mAb

Cat No.: ARM2784
Size:
Product Name: PKC delta Recombinant Rabbit mAb
Cat No.: ARM2784
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB, IHC, ICC/IF, FC
clonality: Monoclonal
recommended dilution: WB, IHC, ICC/IF, FC
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human PKC delta
calculated molecular weight: 78 kDa
observed molecular weight: 78 kDa
genbank accession number: P28867
gene id (ncbi): 18753
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: Pkcd; PKC[d]; AI385711; PKCdelta; D14Ertd420e
category: Primary Ab
concentration: 1mg/ml
background: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Negatively regulates B cell proliferation and also has an important function in self-antigen induced B cell tolerance induction. Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis.