DDIT3 Recombinant Rabbit mAb
Cat No.: ARM2776
Size:
Product Name: | DDIT3 Recombinant Rabbit mAb |
Cat No.: | ARM2776 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB, IHC |
clonality: | Monoclonal |
recommended dilution: | WB, IHC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human DDIT3 |
calculated molecular weight: | 19 kDa |
observed molecular weight: | 27 kDa |
genbank accession number: | P35638 |
gene id (ncbi): | 1649 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CHOP; CEBPZ; CHOP10; CHOP-10; GADD153; C/EBPzeta |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010] |