DYNLL1 Recombinant Rabbit mAb
Cat No.: ARM2758
Size：
| Product Name: | DYNLL1 Recombinant Rabbit mAb |
| Cat No.: | ARM2758 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB, IHC, ICC/IF, FC, IP |
| clonality: | Monoclonal |
| recommended dilution: | WB, IHC, ICC/IF, FC, IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human DYNLL1 |
| calculated molecular weight: | 10 kDa |
| observed molecular weight: | 10 kDa |
| genbank accession number: | P63167 |
| gene id (ncbi): | 8655 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | LC8; PIN; DLC1; DLC8; LC8a; DNCL1; hdlc1; DNCLC1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |