CaMKII alpha Recombinant Rabbit mAb
Cat No.: ARM2756
Size:
Product Name: | CaMKII alpha Recombinant Rabbit mAb |
Cat No.: | ARM2756 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB, IHC, ICC/IF, FC |
clonality: | Monoclonal |
recommended dilution: | WB, IHC, ICC/IF, FC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CaMKII |
calculated molecular weight: | 54 kDa |
observed molecular weight: | 54 kDa |
genbank accession number: | Q9UQM7 |
gene id (ncbi): | 815 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CAMKA |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008] |