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LIS1 Recombinant Rabbit mAb

Cat No.: ARM2728
Size:
Product Name: LIS1 Recombinant Rabbit mAb
Cat No.: ARM2728
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB, FC, IP
clonality: Monoclonal
recommended dilution: WB, FC, IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human LIS1
calculated molecular weight: 47 kDa
observed molecular weight: 47 kDa
genbank accession number: P43034
gene id (ncbi): 5048
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MDS; LIS1; LIS2; MDCR; NudF; PAFAH
category: Primary Ab
concentration: 1mg/ml
background: This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]