FKBP51 Recombinant Rabbit mAb
Cat No.: ARM2699
Size:
Product Name: | FKBP51 Recombinant Rabbit mAb |
Cat No.: | ARM2699 |
source: | Rabbit |
reactivity: | Human, Rat |
applications: | WB, IHC, ICC/IF, FC, IP |
clonality: | Monoclonal |
recommended dilution: | WB, IHC, ICC/IF, FC, IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human FKBP51 |
calculated molecular weight: | 51 kDa |
observed molecular weight: | 51 kDa |
genbank accession number: | Q13451 |
gene id (ncbi): | 2289 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | P54; AIG6; FKBP51; FKBP54; PPIase; Ptg-10 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] |