SERCA2 ATPase Recombinant Rabbit mAb
Cat No.: ARM2689
Size：
| Product Name: | SERCA2 ATPase Recombinant Rabbit mAb |
| Cat No.: | ARM2689 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB, IHC, ICC/IF, FC |
| clonality: | Monoclonal |
| recommended dilution: | WB, IHC, ICC/IF, FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human SERCA2 ATPase |
| calculated molecular weight: | 115 kDa |
| observed molecular weight: | 115 kDa |
| genbank accession number: | P16615 |
| gene id (ncbi): | 488 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DD; DAR; ATP2B; SERCA2 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008] |